Clinical Pharmacology

Pharmacogenomics at the Crossroads: Closing the Gap Between Genetic Evidence and Everyday Prescribing

Pharmacogenomic testing offers clinicians an unprecedented window into individual drug metabolism, yet widespread adoption in routine practice remains elusive. This article examines the structural, financial, and educational barriers that prevent CYP450 and TPMT testing from becoming standard of care—and offers practical frameworks for integrating genetic data into clinical workflows today.

Jul 27, 2026

When Medications Collide: A Clinician's Guide to Cytochrome P450 Interactions in High-Risk Polypharmacy Regimens

Cytochrome P450 enzyme interactions remain one of the most underrecognized drivers of adverse drug reactions in patients managing multiple medications. This resource equips prescribers with structured tools for identifying, assessing, and mitigating high-risk CYP450 interactions before patient harm occurs. From real-world clinical scenarios to evidence-based deprescribing frameworks, this guide bridges pharmacokinetic theory and frontline practice.

Jul 27, 2026